本帖最后由 橙色雨丝 于 2015-8-5 16:11 编辑
不知道你是否看得懂英文，附上一篇来自世界卫生组织（WHO）网站，由国际抗癌联盟（UICC）专家撰写的关于弥漫大B淋巴瘤的文章，文章的前言是：
DIFFUSE LARGE B-CELL LYMPHOMA Union for International Cancer Control 2014 Review of Cancer Medicines on the WHO List of Essential Medicines
DIFFUSE LARGE B-CELL LYMPHOMA Executive Summary
Diffuse large B-cell lymphoma (DLBCL) is the most common subtype of non-Hodgkin lymphoma (NHL), constituting up to 40%of all cases globally.[1] This subtype of cancer is heterogeneous and aggressive, yet scientific advances in the last quarter century have rendered it curable with chemotherapy or with combined chemotherapy and immunotherapy.Until 1998, the standard regimen for DLBCL treatment included cyclophosphamide,vincristine, doxorubicin, and prednisone, referred to as “CHOP.” The standard of care in the United States, Europe, and other high-income settings now includes a combination of the four chemotherapy drugs plus immunotherapy withthe humanized monoclonal antibody directed at CD20, rituximab (R-CHOP). Research demonstrates 55.8% survival at 6 years among patients receiving CHOP only, and74.3% among patients on R-CHOP. [2] The chance of survival without chemotherapy is 0%.Thus, with the addition of CHOP alone, gains in survival go from 0% to56%. Drugs comprising CHOP are all old, off-patent drugs, while rituximab remains on patent, is more costly, and technically more difficult to administer. Adding rituximab to CHOP results in an increase in long-term survival of almost 20%. We are recommending that rituximab be added to the Essential Medicines List and that R-CHOP be viewed as the standard regimen for this disease. In settings where rituximab is not available, CHOP should still be utilized since many patients will benefit from its use.
注意红字的部分：过去的25年在科学上的进步使得这种疾病可以通过化疗和或化疗联合免疫治疗而治愈......研究证明接受CHOP方案治疗的病人6年生存率是55.8%，而接受R-CHOP方案的病人则为74.3%。不做化疗的生存的机会是0%。
国际抗癌联盟创立于1933年，是拥有来自80个以上国家，超过270个会员组织的独立、非政府的协会。国际抗癌联盟为联合国经济社会委员会(UN Economic and Social Council)的咨询机构，也与世界卫生组织、国际癌症研究组织和由国际原子能组织所发起的癌症治疗行动计划有着密切的合作。你觉得这样一个国际机构会拿这么重要的事情开玩笑吗？
DiffuseLargeBCellLymphoma.pdf
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雷达卡
发表于 2015-8-4 08:38:56
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雨丝兄弟的文章总是深入浅出。膜拜！
