霍奇金混合细胞型活的够久 就一定会复发 是这样吗？

不美丽

今天听大夫跟别人家属说只要活的够久  就一定会复发  是这样吗？  还有五年存活率是啥意思

智由

霍奇金治愈率很高，要相信医生，相信自己！这种说法应该没有科学道理。

六日

什么大夫？听着像是巫医

zhangqingbinsc

这种事很难讲。在国内，因为失访很常见，所以能有个五年生存率就很不错了，跟踪到十年，且失访率在合理范围内的，我生病三年多了，是没有看到过。再进一步，霍奇金绝大多数都是年轻病人，二十多岁叫做年轻，三十多岁还是年轻。真正让人放心的生存率数据，恐怕要在25年以上，但那个国内真没有，现在开始做都没条件。况且这当中除了复发死亡，还有因治疗带来的第二肿瘤和心血管疾病死亡。对于霍奇金淋巴瘤，特别是早期的没做过移植甚至没做放疗的，单独拿出来，每一种风险都不大，但是林林总总加起来，恐怕二十多岁发病的病人，到了六十岁，与普通人的生存率差别会非常大。但是，即使这样，霍奇金淋巴瘤在所有癌症中的治疗效果，是最好的那一部分了，科技水平就是这样，个人又有什么办法呢？

橙色雨丝

zhangqingbinsc 发表于 2017-10-30 23:02
这种事很难讲。在国内，因为失访很常见，所以能有个五年生存率就很不错了，跟踪到十年，且失访率在合理范围 ...

Hodgkin disease (1973–2002): long-term survival and cure fractionsGeorge Bouliotis Medical Research Council Midlands Hub for Trials Methodology Research, University of Birmingham, Birmingham, UK & Eric M. Bessell Department of Clinical Oncology, Nottingham City Hospital, Nottingham, UKCorrespondenceebessell@hotmail.co.uk

Abstract

The Nottinghamshire Lymphoma Registry contains the details of all patients diagnosed with lymphoma (since 1 January 1973) within a defined geographical area with a stable population of 1.1 million. The aim of this study was to investigate the relative survival and estimate the cure fraction for patients with Hodgkin disease (HD) using various cure fraction models. Five- and 10-year survival was estimated in comparison to the general population of the same age, gender and year of diagnosis. Relative survival probabilities at 10 years were 52.3% for the 1973–1982 cohort, 67.8% (1983–1992) and 75.7% (1993–2002). The estimated cured fraction (π) was 45%, 65% and 75%, respectively, for the same cohorts. There was very little excess mortality after 4 years from treatment. The prognosis of patients with HD has improved progressively within a defined unselected population over this 30-year period. In the 1993–2002 cohort the prognosis after 4 years of treatment is almost the same as for a normal population.

早些年间霍奇金治疗毒性较大，特别是放疗技术不好，所以远期副作用大，影响总生存率。不过，现在无论是化疗还是放疗技术都有了长足的进步，远期风险已经很小，比如说根据英国的一项研究，1993年-2002年期间治疗的霍奇金患者，如果四年内没有复发，其预期寿命基本与正常人群相当。

不美丽

橙色雨丝 发表于 2017-10-31 08:44
Hodgkin disease (1973–2002): long-term survival and cure fractionsGeorge Bouliotis Medical Researc ...

雨丝大神永远不会让人失望

我❤️小顾

雨丝太棒了

Freely

看了立马又有信心了！